Funding for this research was provided by:
Cambridge Biomedical Research Centre (N/A)
Received: 22 July 2019
Accepted: 15 November 2019
First Online: 19 December 2019
Ethics approval and consent to participate
: All procedures performed in this study involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. Informed consent was obtained from all individual participants included in the study.
: Participants gave explicit consent to publishing of results.
: MdG, NP, RLJ, DG, DF, PM, AW, NW and PJR are or were employees of GSK and hold shares in GSK. RM, AÖ, MJG and TDF declare that they have no competing interests. MB is an external consultant to GSK. AR was an employee of Bioxydyn Ltd, held stock options in Bioxydyn Ltd, was an employee of GSK and is an external consultant to GSK. YK is an employee of GSK.