Funding for this research was provided by:
Ministry of Education, Culture, Sports, Science and Technology (16K10428)
Received: 7 October 2019
Accepted: 21 November 2019
First Online: 4 December 2019
Ethics approval and consent to participate
: All procedures involving human participants were performed in accordance with the ethical standards of the Institutional Research Committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. The Ethics Committee of Hokkaido University Hospital approved this study (#012-0406), and written informed consent to participate was obtained from each subject.
: Not applicable
: This work was supported by a grant from the Creation of Innovation Centers for Advanced Interdisciplinary Research Areas Program from the Ministry of Education, Culture, Sports, Science, and Technology-Japan and the Japan Society for the Promotion of Science (JSPS) KAKENHI (no. 16K10428) of Japan's Ministry of Education, Culture, Sports, Science, and Technology.