Funding for this research was provided by:
Received: 3 March 2021
Accepted: 17 May 2021
First Online: 2 June 2021
: The study protocol was approved by the institutional review boards of each participating center, and competing authorities.
: All patients gave written informed consent for study participation.
: Holger Amthauer: Grants: Sirtex, Bayer. Personal fees: Sirtex, GE Healthcare, Novartis, outside the submitted work. Kerstin Schütte: Personal fees: Bayer. Peter Malfertheiner: Grants: Bayer, Sirtex. Heinz Josef Klümpen: Grants: Bayer, Personal fees: Ipsen, outside the submitted work. Bruno Sangro: Personal fees: Sirtex, BTG, Bayer, BMS, Astra Zeneca, Eli Lilly, Merck, Novartis, Terumo, Adaptimmune; Non-financial support: Sirtex, BMS, outside the submitted work. Maciej Pech: Grants: Sirtex, Bayer; Personal fees: Sirtex. Peter Bartenstein: Grants: Sirtex. Jens Ricke: Grants: Sirtex, Bayer; Personal fees: Sirtex, Bayer. Max Seidensticker: Personal fees: Bayer, Sirtex.