Funding for this research was provided by:
Natural Science Foundation of Shandong Province (ZR2019ZD24, ZR2019YQ30)
Received: 5 May 2021
Accepted: 12 September 2021
First Online: 30 October 2021
: Animal use procedures were in accordance with the recommendations of the European regulations (EU Directive 2010/63) approved by the Laboratory Animal Use and Management Committee of Jiangsu KMQ Biotech Co., Ltd. (IACUC No.: KMQ-CLI001001 for non-human primate studies) and Suzhou GenePharma Co., Ltd. (IACUC No.: 2020265 for mouse studies).
: None of the authors have any conflicts of interest to declare. Chao Wang and Yan Sun were employed by SmartNuclide biopharma Co., Ltd (SuZhou, China). The remaining authors declare that the research was conducted without any commercial or financial relationships that could be construed as a potential conflict of interest.