Article History
Received: 8 May 2019
Accepted: 4 December 2019
First Online: 17 December 2019
Ethics approval and consent to participate
: The study is not a clinical trial and uses only aggregated publicly available metadata, so there is no need for an ethics approval and a consent to participate.
: All authors confirm that they have approved the manuscript for submission and subsequent publication.
: CMD is next to his academic affiliation employed by Bayer Vital GmbH. FW was a trainee at Bayer Vital GmbH during the preparation of the manuscript. JR is offering by r-connect ltd consultancy to pharmaceutical companies. MH is working for ClinStat GmbH, a service provider offering statistical support to different pharmaceutical companies.