Funding for this research was provided by:
Fundação para a Ciência e Tecnologia (PD/BD/113665/2015)
COMPETE 2020 and Fundação para a Ciência e Tecnologia (POCI-01-0145-FEDER-029130)
Received: 10 May 2019
Accepted: 10 September 2019
First Online: 23 September 2019
Ethics approval and consent to participate
: Not applicable. Data had previously been anonymised.
: Not applicable.
: JAF received personal fees outside the submitted work from AstraZeneca, GSK, Mundipharma, Novartis, Teva. All other authors declare that they have no competing interests.