Fage, Nicolas
Demiselle, Julien
Seegers, Valérie
Merdji, Hamid
Grelon, Fabien
Mégarbane, Bruno
Anguel, Nadia
Mira, Jean-Paul
Dequin, Pierre-François
Gergaud, Soizic
Weiss, Nicolas
Legay, François
Le Tulzo, Yves
Conrad, Marie
Coudroy, Remi
Gonzalez, Frédéric
Guitton, Christophe
Tamion, Fabienne
Tonnelier, Jean-Marie
Bedos, Jean Pierre
Van Der Linden, Thierry
Vieillard-Baron, Antoine
Mariotte, Eric
Pradel, Gaël
Lesieur, Olivier
Ricard, Jean-Damien
Hervé, Fabien
Du Cheyron, Damien
Guerin, Claude
Mercat, Alain
Teboul, Jean-Louis
Radermacher, Peter
Asfar, Pierre http://orcid.org/0000-0002-1175-9149
Funding for this research was provided by:
Ministère de l'Enseignement Supérieur et de la Recherche
Article History
Received: 3 August 2022
Accepted: 8 August 2022
First Online: 19 August 2022
Declarations
:
: The SEPSISPAM trial (NCT01149278) was approved for all participating centers by the ethic committee at the Angers University Hospital. Written informed consent was obtained from all patients, their next of kin or another surrogate decision-maker, as appropriate. In accordance with ethics policy, if patients were unable to provide informed consent and the next of kin or a designated person was not available, the emergency inclusion procedure was applied and post hoc consent was obtained from patients who survived.
: Not applicable.
: Dr. Weiss received consultant fees from Med-Day Pharmaceuticals beyond the scope of this article. Dr. Dequin's institution received funding from Angers University Hospital, the French Ministry of Health, Abionic, Atox Bio, Sphingotec GMBH, Adrenomed, Medspace, Aridis, Merck, Combioxin, GSK, Med-Immune, Genentech INH, Rev-Immune, Faron, Kenta and Tigenix. He also received support for article research from the French Ministry of Health. Dr. Gonzalez disclosed work for hire. Dr. Teboul received funding from Getinge/Pulsion. Dr. Radermacher's institution received funding from Deutsche Forschungsgemeinschaft and the German Ministry of Defence. The remaining authors have disclosed that they do not have any potential conflicts of interest.