Received: 7 September 2021
Accepted: 31 January 2022
First Online: 1 April 2022
: All animal protocols were conducted under the guidelines established in the Guide for the Care and Use of Laboratory Animals (National Institutes of Health, Publication No. 85–23, Revised, by the U.S. Department of Agriculture (USDA) in the Animal Welfare Act (Public Law 99–198), and were carried out under the supervision of the Fudan University Institutional Animal Care and Use Committee (IACUC) (approval number: 20200306–016), Shanghai Mincal Medical Research Co. IACUC (approval number: 201808–10), WuXi AppTec (Shanghai, China) IACUC, or the JOINN Laboratories IACUC (Suzhou, China).
: Not applicable.
: J.Q. and Y.L. are the founders and shareholders of ZheJiang HygeianCells Biomedical Co. F.Z. is an employee of Shanghai Mincal Medical Research Co., Ltd. Large Animal Research Center, and performed the swine study as a CRO service. J.Q., N.S., B.C., Y.Z., X.G., L.Z., K.C., J.X., and J.W. are inventors in patent applications. All other authors declare no competing interests.