Funding for this research was provided by:
Natural Science Foundation of Hebei Province (81771233, 82171290)
Research and Promotion Program of Appropriate Techniques for Intervention of Chinese High-risk Stroke People (GN-2020R0007)
BTH Coordinated Development-Beijing Science and Technology Planning Project (Z181100009618035)
Beijing Municipal Administration of Hospitals' Ascent Plan (DFL20190501)
Beijing Natural Science Foundation (19L2013; 22G10396)
Received: 1 September 2022
Accepted: 30 December 2022
First Online: 18 January 2023
: The MIMIC-IV database was built by the Massachusetts Institute of Technology and was approved to waive the documentation of informed consent by the Institutional Review Boards of Beth Israel Deaconess Medical Center. The eICU-CRD study was exempt from institutional review board approval due to the retrospective design, lack of direct patient intervention, and the security schema, for which the re-identification risk was certified as meeting safe harbor standards by an independent privacy expert (Privacert, Cambridge, MA) (Health Insurance Portability and Accountability Act Certification no. 1031219-2). To access the database, X. T. completed the Collaborative Institutional Training Initiative course named “Data or Specimens Only Research” and obtained the certification (certification number: 43334826). There was no requirement for individual informed consent to extract data from the MIMIC-III and eICU-CRD databases because both databases’ information was publicly available, and all patient data were deidentified.
: The authors declare no conflict of interest.