Received: 26 August 2020
Accepted: 11 January 2021
First Online: 9 March 2021
Ethics approval and consent to participate
: Animal procedures were verified by the External Ethical Committee of “Hospital General Universitario de Ciudad Real”, and approved by the Junta de Castilla-La Mancha Animal Welfare department as compliable with the RD 53/2013 of the 1st of February which establishes basic rules applied to protect animals used for research, and other scientific matters like teaching. The regulations conform to the European Directive 2010/63/EU for the Protection of Vertebrate Animals Used for Experimental and Other Scientific Purposes (Brussels, European Union) and achieve the standard of care required by the US Department of Health and Human Services’ Guide for the Care and Use of Laboratory Animals.
: Not applicable.
: The authors declare that they have no competing interests.