Funding for this research was provided by:
Natural Sciences and Engineering Research Council of Canada
Clinical Academic Fellowship from the Chief Scientist Office (CAF/08/01)
Received: 18 July 2017
Accepted: 2 January 2018
First Online: 15 January 2018
Ethics approval and consent to participate
: Ethical approval was granted by North of Scotland Research Ethics Service (09/S0802/24), and written informed consent was obtained from the parents of all subjects. Informed assent was also obtained from older children who were deemed capable of understanding the nature of the study. This study is publicly registered on the United Kingdom Clinical Research Network Portfolio (9633). An ethics amendment allowed further review of the cohort participants’ therapies and clinical response for the first year following diagnosis.
: Not applicable
: The authors declare that they have no competing interests.
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