Funding for this research was provided by:
Deutsche Forschungsgemeinschaft (EXC306, CRC1182 C2)
Bundesministerium für Forschung und Technologie (SysINFLAME CP3/4)
Received: 22 September 2017
Accepted: 24 January 2018
First Online: 20 February 2018
Ethics approval and consent to participate
: All participants gave informed consent, and the study protocol was approved by the local ethical committee at the Medical Faculty of Christian Albrecht University Kiel (D537/15; D501/14). The study does not contain identifiable information of individual persons.
: Pius Brzoska, Jon Sherlock, and Astrid Ferlinz are employees of Thermo Fisher, but the company did not influence any aspect of the study. The authors declare that they have no competing interests.
: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.