Funding for this research was provided by:
Agence Nationale de la Recherche (10-LABX-69-01)
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (31003A_175603)
Received: 20 March 2019
Accepted: 4 September 2019
First Online: 13 September 2019
Ethics approval and consent to participate
: The clinical study was approved by the Comité de Protection des Personnes - Ouest 6 on June 13, 2012, and by the French Agence Nationale de Sécurité du Médicament on June 22, 2012, and has been performed in accordance with the Declaration of Helsinki. The study is sponsored by the Institut Pasteur (Pasteur ID-RCB Number 2012-A00238-35) and was conducted as a single-center study without any investigational product. The protocol is registered under ClinicalTrials.gov (study number NCT01699893). Informed consent was obtained from the participants after the nature and possible consequences of the studies were explained.
: Not applicable.
: C.H., A.B., and M.L.A. are employees of Genentech Inc., a member of The Roche Group. The other authors declare that they have no competing interests.