Funding for this research was provided by:
National Institutes of Health (U01 AI111598, U01 AI111598, U01 AI111598, U01 AI088654)
National Institutes of Health (HHSN272201400031C)
Received: 4 September 2019
Accepted: 10 February 2020
First Online: 17 March 2020
Ethics approval and consent to participate
: This study was approved by the institutional review boards at the Nicaraguan Ministry of Health, the University of Michigan, and the University of California, Berkeley. Informed consent or parental permission was obtained for all participants.
: Not applicable.
: The authors declare that they have no competing interests.