Funding for this research was provided by:
Natural Science Foundation of Zhejiang Province (ZZYJ-WTRW-2018-01)
National Natural Science Foundation of China (no. 81503527)
Received: 10 December 2019
Accepted: 13 May 2020
First Online: 10 June 2020
Ethics approval and consent to participate
: Nineteen centenarians were chosen. All of them were free of major age-related diseases, i.e., cardiovascular or cerebrovascular disease, cancer, dementia, renal or hepatic failure, etc. They were informed about the study and signed a letter of consent, in accordance with the guidelines of the Ethics Committee of the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China (2015-KL-008-01).
: Not applicable
: The authors declare that they have no competing interests.