Koparir, Asuman http://orcid.org/0009-0002-5222-6848
Lekszas, Caroline http://orcid.org/0000-0003-4074-3776
Keseroglu, Kemal http://orcid.org/0000-0001-5452-4801
Rose, Thalia
Rappl, Lena
Rad, Aboulfazl http://orcid.org/0000-0001-8627-8828
Maroofian, Reza http://orcid.org/0000-0001-6763-1542
Narendran, Nakul http://orcid.org/0000-0002-6356-1433
Hasanzadeh, Atefeh
Karimiani, Ehsan Ghayoor
Boschann, Felix http://orcid.org/0000-0001-9410-9290
Kornak, Uwe http://orcid.org/0000-0002-4582-9838
Klopocki, Eva
Özbudak, Ertuğrul M. http://orcid.org/0000-0003-2858-4696
Vona, Barbara http://orcid.org/0000-0002-6719-3447
Haaf, Thomas http://orcid.org/0000-0002-0737-0763
Liedtke, Daniel http://orcid.org/0000-0003-0934-7169
Funding for this research was provided by:
Deutsche Forschungsgemeinschaft (469177153, 397519724)
Julius-Maximilians-Universität Würzburg
Article History
Received: 26 January 2024
Accepted: 29 February 2024
First Online: 6 March 2024
Declarations
:
: Patient consent to participate in this study was obtained prior to investigation by their parents and/or legal guardians. Ethics approval to this study was given to Dr. Ehsan Ghayoor Karimiani by the regional Ethics Committee in the field of Research in Medical Sciences at Mashhad University of Medical Sciences (Reference number IR.MUMS.REC.1395.40). All procedures involving experimental animals were performed in compliance with local animal welfare laws (Tierschutzgesetz §11, Abs. 1, Nr. 1, husbandry permit number 568/300-1870/13), European Union animal welfare guidelines (EU directive 2010/63/EU), and best-practice scientific policies (ARRIVE guidelines). All presented experiments have been performed in zebrafish embryos younger than 2 dpf and have been terminated timely before free-swimming and independent feeding larval stages (5 dpf) and thereby do not fall into the German regulatory frameworks dealing with animal experimentation. Procedures involving transgenic animals were in addition perform according to local regulations on this topic (Gentechnikrecht/Gentechnik-Sicherheitsverordnung).
: The authors declare no competing interests.