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Article History

Received: 15 December 2017

Accepted: 17 January 2018

First Online: 29 January 2018

Ethics approval and consent to participate

: Retrospective de-identified patient data were collected in compliance with the IRB guidelines of each participating institution and did not require specific approval from an ethics committee. A specific signed patient consent was not required for this retrospective analysis.

: Not applicable.

: Dr. Zhang is a consultant for Bayer and G1 therapeutics, and has received research support from Janssen. Dr. George is a consultant for Bayer, Dendreon, Exelixis, Medivation, Novartis, Pfizer, Sanofi, GSK, Astellas, BMS, Genentech, Janssen, Celgene, Merck, Myovant. Dr. Atkins is a consultant for Genentech, Novartis, X4 Pharma, Genoptix, BMS, Merck, Nektar, Exelixis, Acceleron, Peleton, Eisai, Celldex, Alexion, AstraZeneca, Glactone, Agenus, Idera, Argos, and Array. Dr. Vogelzang is a consultant for Amgen, Cerulean, Pfizer, Bayer, Genentech, Churchill, Heron, AstraZeneca, Caris and Tolero. Dr. Pal is a consultant for Pfizer, Novartis, Aveo, Myriad, Genentech, Exelixis, BMS, Astellas, Ipsen, Eisai and has received research support from Medivation. Dr. Appleman has received research support from Medivation/Astellas. Dr. Gilligan has received travel expenses from WellPoint. Dr. Grivas is a consultant for Genentech, Dendreon, Bayer, Exelixis, Merck, BMS and AstraZeneca. Dr. Garcia is a consultant for Sanofi, Pfizer, Bayer, Eisai, Exelixis, Medivation and Genentech. Dr. Rini has received research funding from BMS. The other authors have declared no relevant competing interests related to this manuscript.

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