Funding for this research was provided by:
Merck KGaA, Darmstadt, Germany
Received: 19 July 2018
Accepted: 20 November 2018
First Online: 16 January 2019
Ethics approval and consent to participate
: All patients were enrolled in accordance with approved protocols, international standards of good clinical practice, institutional review board approvals, and institutional safety monitoring. Written informed consent was provided.
: Not applicable.
: UK has received honoraria from and is a member of advisory boards for AstraZeneca; Bristol-Myers Squibb; Merck, Sharp & Dohme; Merck KGaA; and Pfizer.JMM reports consultancy for Merck, Sharp & Dohme and Amgen; reimbursement for travel and accommodations from EMD Serono and Merck, Sharp & Dohme; other relationships with Amgen, EMD Serono, and Merck KGaA; honoraria from Genentech and EMD Serono; JMM’s institution received research funding from Merck KGaA, Sanofi, Novartis, Polynoma, Immunocore, Amgen, and AstraZeneca.SB has received honoraria from Pharmamar, GlaxoSmithKline, Pfizer, and Bayer; has received research support from Novartis, Blueprint Medicines, and Ariad; reports consultancy for GlaxoSmithKline, Novartis, Pfizer, Bayer, Fresenius, Lilly, Blueprint Medicines, and Deciphera; and received travel support from Pharmamar and Bayer.HB has nothing to disclose.MRP is a member of an advisory board for Guardant and speaker’s bureau for Exelixis, Bristol-Myers Squibb, Medivation, Genentech, and Gilead.DG has nothing to disclose.JJN has nothing to disclose.MHT has received honoraria from Blueprint Medicines, Trillium Pharma, Bristol-Myers Squibb, and Eisai; is a member of an advisory board for Blueprint Medicines and speaker’s bureau for Eisai; and reports consultancy for Trillium Pharma and Bristol-Myers Squibb.LW reports consultancy for and has received honoraria from Amgen, Roche, and Merck.KWL’s institution received research funds from AstraZeneca, Daiichi Sankyo, Five Prime Therapeutics, Green Cross Corp., Macrogenics, Merck KGaA, Merck & Co., Ono Pharmaceutical and Taiho Pharmaceutical.VK is employed by EMD Serono.KC is employed by EMD Serono.AvH is employed by Merck KGaA.JLG has nothing to disclose.
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