Funding for this research was provided by:
Grant Agency of Charles University (344216, 668217)
Czech Health Research Council of the Ministry of Health of the Czech Republic (16-28594A, 16-2860)
European Regional Development Fund-Project BBMRI-CZ (No: EF16 013/0001674)
Received: 15 May 2019
Accepted: 30 August 2019
First Online: 17 October 2019
Ethics approval and consent to participate
: All patient studies were approved by the Ethics Committee of the University Hospital Hradec Králové and the Ethics Committee of the University Hospital Motol. All of the patients signed an informed consent prior to inclusion to the study.
: Not applicable.
: The authors declare that they have no competing interests.