Funding for this research was provided by:
Wellcome Trust (105104/Z/14/Z)
Cancer Research UK (C43396/A18377)
European Research Council (820137)
Text and Data Mining valid from 2019-11-18
Received: 13 June 2019
Accepted: 2 October 2019
First Online: 18 November 2019
Ethics approval and consent to participate
: Human samples were obtained from clinical trial protocols which have been approved by the UK National Ethics Committee (Prospect C trial approval number: 12/LO/0914, Prospect R trial approval number: 14/LO/1812, FOrMAT trial approval number 13/LO/1274). All individuals provided written informed consent for sample donation and use for research.
: All authors read and approved the final manuscript for publication.
: The authors have no relevant competing interests to declare.