Funding for this research was provided by:
Japan Society for the Promotion of Science (16J06511, 23590124, 16K07211)
Japan Agency for Medical Research and Development (15ek0109040h0002)
Received: 6 October 2017
Accepted: 19 November 2017
First Online: 30 November 2017
: The authors declare that they have no competing interests.
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