Funding for this research was provided by:
National Natural Science Foundation of China (31430037, 91542201, 81590765, 31670883, 31500145)
Shanghai Brain-Intelligence Project from the Shanghai Science and Technology Committee (16JC1420500)
Beijing Brain Project (Z161100002616004)
Ministry of Science and Technology (2014CB942801, 2012YQ03026006)
the CAMS Initiative for Innovative Medicine (2016-I2M-1-005)
NIH R01 (AI056154, AI078389)
PUMC Youth Fund (3332016125)
Received: 15 July 2018
Accepted: 17 July 2018
First Online: 10 August 2018
Ethics approval and consent to participate
: This study was carried out in strict accordance with the recommendations in the protocols approved by the Institutional Animal Care and Use Committee at the Institute of Genetics and Developmental Biology, Chinese Academy of Science (Approval Number: AP2017013) and the Animal Experiment Committee of the Laboratory Animal Center, Academy of Military Medical Sciences, China (Approval Number: IACUC-13-2016-001). Intracranial injections and dissections were performed under anesthesia that was induced and maintained by 2, 2, 2 - Tribromoethanol. All efforts were made to obey 3R principles (Replacement, Reduction, and Refinement) and to minimize suffering.
: Not applicable.
: The authors declare that they have no competing interests.
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