Funding for this research was provided by:
Japan Agency for Medical Research and Development (17km0405206h0002)
JSPS KAKENHI (20790625, 22790829, 16K09676, 18K07536, 16K09678, 16K09700, 18H04043)
Received: 4 October 2018
Accepted: 11 October 2018
First Online: 17 October 2018
Ethics approval and consent to participate
: This study was approved by the ethics committee of the Juntendo University School of Medicine, in accordance with The Code of Ethics of the World Medical Association (Declaration of Helsinki).
: All participants for genetic and clinical analyses gave full written informed consent before participation.
: The authors declare that they have no competing interests.
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