Funding for this research was provided by:
Japan Society for the Promotion of Science (17H04986, 18H04860)
Uehara Memorial Foundation (none)
Received: 27 June 2019
Accepted: 18 July 2019
First Online: 25 July 2019
Ethics approval and consent to participate
: All the experiments were conducted in compliance with the ARRIVE guidelines. The experiments using genetically modified mice were approved by the Animal Care and Use Committee and the recombinant DNA experiment committee of Nagoya University (approval numbers #19269 and #143, respectively).
: The authors declare that they have no competing interests.