Funding for this research was provided by:
Medical Research Council
Barts and The London Charity
Received: 28 August 2019
Accepted: 13 October 2019
First Online: 8 November 2019
Ethics approval and consent to participate
: This study was approved by the Medical Research Ethics Committee (MREC No. 06/Q0104/133). All patients gave written informed consent.
: Not applicable.
: The authors declare that they have no competing interests.