Funding for this research was provided by:
Multiple System Atrophy Trust (N/A)
British Neuropsychological Society (N/A)
Medical Research Foundation (N013255/1)
National Institute of Neurological Disorders and Stroke (R21-NS093222, U24 NS072026)
National Institute on Aging (P30 AG19610)
Arizona Department of Health Services (contract 211002)
Arizona Biomedical Research Commission (contracts 4001, 0011, 05-901 and 1001)
Alzheimer’s Research UK
Reta Lila Weston Trust (N/A)
MSA Coalition (N/A)
Received: 6 April 2020
Accepted: 7 May 2020
First Online: 14 May 2020
Ethics approval and consent to participate
: All brain tissue from brains donated to the Queen Square Brain Bank (QSBB) archives (UK), including the tissue used for the DNA methylation study, is stored under a licence from the Human Tissue authority (No. 12198). The QSBB brain donation programme and protocols have received ethical approval for donation and research by the NRES Committee London – Central [18/LO/0721]. For the RNAseq study, conducted in the USA, all human samples were derived from autopsy tissue and were classified as non-human subject research material according to local regulations.
: Not applicable.
: The authors declare that they have no conflict of interest.