Funding for this research was provided by:
Alzheimer Forschung Initiative (#12854 and #17011)
Deutsche Forschungsgemeinschaft (#WA1477/6-3)
National Institute on Aging (R01 AG040092 and R01/RF1 AG058657)
Received: 17 April 2020
Accepted: 30 May 2020
First Online: 29 July 2020
Ethics approval and consent to participate
: Human brain tissue was collected at the time of autopsy, having obtained prior consent from the next of kin and following protocols approved by the Partners Human Research Committee at Brigham and Women’s Hospital (Boston, MA, USA). All procedures and use of mice at Brigham and Women’s Hospital was approved by the Harvard Medical Area Standing Committee on animals and was in compliance with state and federal regulations.
: Not applicable.
: The authors declare that they have no competing or conflict of interests.