Funding for this research was provided by:
National Institute of Neurological Disorders and Stroke (R01NS097721)
Boehringer Ingelheim Fonds
Received: 23 October 2020
Accepted: 26 February 2021
First Online: 10 March 2021
Availability of data and material
: The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.
: The authors have no competing interests, and the content of this manuscript has not been published, or submitted for publication elsewhere.
: All authors have seen and approved the manuscript and have adhered to the standards of the National Research Council’s Guide for the care and use of laboratory animals and the ARRIVE guidelines.
: All procedures were approved by the Washington University Animal Studies Committee (Protocol 20190223) and are consistent with the National Institutes of Health guidelines for the care and use of animals.