Valentino, Rebecca R.
Ramnarine, Chloe
Heckman, Michael G.
Johnson, Patrick W.
Soto-Beasley, Alexandra I.
Walton, Ronald L.
Koga, Shunsuke
Kasanuki, Koji
Murray, Melissa E.
Uitti, Ryan J.
Fields, Julie A.
Botha, Hugo
Ramanan, Vijay K.
Kantarci, Kejal
Lowe, Val J.
Jack, Clifford R.
Ertekin-Taner, Nilufer
Savica, Rodolfo
Graff-Radford, Jonathan
Petersen, Ronald C.
Parisi, Joseph E.
Reichard, R. Ross
Graff-Radford, Neill R.
Ferman, Tanis J.
Boeve, Bradley F.
Wszolek, Zbigniew K.
Dickson, Dennis W.
Ross, Owen A. http://orcid.org/0000-0003-4813-756X
Funding for this research was provided by:
JSPS KAKENHI (19K17119)
Florida Department of State (20A22)
LEADS Neuropathology Core (U01AG057195)
Chan Zuckerberg Initiative
National Institute on Aging (U54AG 44170, RF1AG 57547, U19AG 63911, R01AG 68128, U01AG 45390, R43AG 65088, U19 AG63911-02, P30 AG62677-02, U01 AG046139, RF1 AG051504, R01 AG051504)
National Institute of Neurological Disorders and Stroke (UH3NS 95495, U01NS 100620, RO3 NS114365-01, U54-NS100693, U54-NS100693)
Boston Scientific Corporation
PCORI (CER-1306-01897)
National Institute on Deafness and Other Communication Disorders (R01 DC12519-06)
Foundation for the National Institutes of Health (P30 AG62677, U01 NS100620, RF1 AG57547, P30 AG62677, U01 NS100620, R34 AG056639, UG3-NS104095, UG3-NS104095, P30 AG062677, U54-NS100693, P01-AG003949, P50-NS072187, R01- NS078086, U54-NS100693, U54- NS110435)
Alzheimer's Drug Discovery Foundation
Robert H. and Clarice Smith and Abigail Van Buren Alzheimer s Disease Research Program of the Mayo Foundation
Schuller Foundation
Katrine B. Andersen Professorship
GHR Foundation
Alexander Family Alzheimer’s Disease Research Professorship of the Mayo Clinic
Mayo Clinic
National Heart, Lung, and Blood Institute
Alzheimer’s Disease Research Center, University of Washington
Lewy Body Dementia Association
Mayo Clinic Dorothy and Harry T. Mangurian Jr. Lewy Body Dementia Program
Little Family Foundation
Turner Foundation
Mayo Clinic Center for Regenerative Medicine
Mayo Clinic in Florida Focused Research Team Program
Sol Goldman Charitable Trust
Donald G. and Jodi P. Heeringa Family
Haworth Family Professorship in Neurodegenerative Diseases fund
Albertson Parkinson's Research Foundation
CurePSP
Tau Consortium
Robert E. Jacoby Professorship
U.S. Department of Defense (W81XWH-17-1-0249)
Michael J. Fox Foundation for Parkinson's Research
Mangurian Foundation Lewy Body Dementia Program at Mayo Clinic
Center for Individualized Medicine, Mayo Clinic
Rainwater Charitable Foundation
Article History
Received: 26 April 2022
Accepted: 18 June 2022
First Online: 14 July 2022
Declarations
:
: This research was approved by the Mayo Clinic Institutional Review Board and all human participants involved in this work provided written consent prior to study commencement.
: Not applicable.
: Melissa E. Murray personally receives consulting fees from VID Radiopharmaceuticals and has received reimbursements for Mild Cognitive Impairment and NIH study section. MEM is also Co-chair of Digital Pathology working group, Chair/Immediate Past Chair of Atypical Alzheimer's disease Professional Interest Area group and is on the organizing committee of the Southeastern Neurodegeneration Conference. Julie A. Fields is on the Oversight and Monitoring Board for the SWAN-Aging study that is funded by the NIA but receives no compensation. Hugo Botha received free AAN registration for the Geschwind Award. Vijay K. Ramanan consults for Bayer Schering Pharma, Piramal Life Sciences, Life Molecular Imaging, Eisai Inc., AVID Radiopharmaceuticals, and Merck Research, and receives research support from GE Healthcare, Siemens Molecular Imaging, and AVID Radiopharmaceuticals. Kejal Kantarci consults Biogen Inc, and receives research support from Avid Radiopharmaceuticals and Eli Lilly, and funding from NIH and Alzheimer’s Drug Discovery Foundation. Val J. Lowe receives research support from AVID Radiopharmaceuticals and Siemens Healthcare and is a consultant for AVID Radiopharmaceuticals, Eisai, Inc., Bayer Schering Pharma, and Merck Research. Clifford R. Jack is on the Roche advisory board but receives no payments. CRJ is also on the writing committee for the NIA AA research framework. Jonathan Graff-Radford has received payment from American Academy of Neurology for lecturing. Nilufer Ertekin-Taner received payments as a conference speaker for 11th ISABS and the Department of Electrical and Computer Engineering and Computer Science, University of Urbana-Champaigne, and additionally for being a visiting professor at the Department of Neurology, Indiana University School of Medicine, Bloomington, Indiana, as well as at National Center for Geriatrics and Gerontology Nagoya, Japan. NET is a Framingham Heat Study Executive Board member and NIH/NIA TREAT-AD external advisory Board member. Jonathan Graff-Radford received a payment from American Academy of Neurology for presenting a lecture. Ronald C. Petersen receives royalties from Oxford University Press in UpToDate and consulting fees from Roche, Merck, Biogen, Genentech, and Eisai. RCP is also on the Genentech DSMB advisory board. R. Ross Reichard is the President of American Association of Neuropathologists. Neill R. Graff-Radford receives research support from multicenter studies with Biogen, Abbvie, Lilly, and Novartis, and receives personal royalties for a chapter on NPH in UpToDate. Bradley F. Boeve has served as an investigator for clinical trials sponsored by Biogen, Alector, and EIP Pharma, and serves on the Scientific Advisory Board of the Tau Consortium. Zbigniew K. Wszolek serves as PI or Co-PI on Biohaven Pharmaceuticals, Inc. (BHV4157-206 and BHV3241-301) and Neuraly, Inc. (NLY01-PD-1), and serves as Co-PI of the Mayo Clinic APDA Center for Advanced Research and as an external advisory board member for the Vigil Neuroscience, Inc. All other authors declare that they have no competing interests to report.