Received: 4 November 2020
Accepted: 17 February 2021
First Online: 26 March 2021
Ethics approval and consent to participate
: This is a retrospective analysis of previously prospectively gathered data. For this type of study formal consent is not required. However, written consent and approval of the previous studies including the same patients was given by both patients and the local Addenbrooke’s Research Ethics Committee, respectively.
: Not applicable.
: All authors except for MC and PS certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers' bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript. MC and PS have financial interests in part of the licensing fees for the software ICM + used in this project for data collection and analysis.