Piccardi, Margherita
Gentiluomo, Manuel
Bertoncini, Stefania
Pezzilli, Raffaele
Erőss, Bálint
Bunduc, Stefania
Uzunoglu, Faik G.
Talar-Wojnarowska, Renata
Vanagas, Tomas
Sperti, Cosimo
Oliverius, Martin
Aoki, Mateus Nóbrega
Ermini, Stefano
Hussein, Tamás
Boggi, Ugo
Jamroziak, Krzysztof
Maiello, Evaristo
Morelli, Luca
Vodickova, Ludmila
Di Franco, Gregorio
Landi, Stefano
Szentesi, Andrea
Lovecek, Martin
Puzzono, Marta
Tavano, Francesca
van Laarhoven, Hanneke W. M.
Zerbi, Alessandro
Mohelnikova-Duchonova, Beatrice
Stocker, Hannah
Costello, Eithne
Capurso, Gabriele
Ginocchi, Laura
Lawlor, Rita T.
Vanella, Giuseppe
Bazzocchi, Francesca
Izbicki, Jakob R.
Latiano, Anna
Bueno-de-Mesquita, Bas
Ponz de Leon Pisani, Ruggero
Schöttker, Ben
Soucek, Pavel
Hegyi, Péter
Gazouli, Maria
Hackert, Thilo
Kupcinskas, Juozas
Poskiene, Lina
Tacelli, Matteo
Roth, Susanne
Carrara, Silvia
Perri, Francesco
Hlavac, Viktor
Theodoropoulos, George E.
Busch, Olivier R.
Mambrini, Andrea
van Eijck, Casper H. J.
Arcidiacono, Paolo
Scarpa, Aldo
Pasquali, Claudio
Basso, Daniela
Lucchesi, Maurizio
Milanetto, Anna Caterina
Neoptolemos, John P.
Cavestro, Giulia Martina
Janciauskas, Dainius
Chen, Xuechen
Chammas, Roger
Goetz, Mara
Brenner, Hermann
Archibugi, Livia
Dannemann, Michael
Canzian, Federico
Tofanelli, Sergio
Campa, Daniele
Funding for this research was provided by:
Associazione Italiana Ricerca Cancro (AIRC IG n.26343)
Italian Ministry of Health (FIMPCUP_J38D19000690001)
Ministry of Health of the Czech Republic (NV19-08-00113)
Cancer Research UK (C7690/A26881)
Pancreatic Cancer UK Research Innovation Fund
Charles University Research Fund (Cooperatio No. 43 -Surgical Disciplines)
Ministry of Health of the Czech Republic (AZV NU21-07-00247, NV19-03-00097)
Italian Ministry of Health grants to Fondazione “Casa Sollievo della Sofferenza” IRCCS Hospital, San Giovanni Rotondo (FG), Italy
“5x1000” voluntary contribution
Article History
Received: 30 June 2022
Accepted: 20 July 2023
First Online: 13 August 2023
Declarations
:
: Individual-level genotyping data were used in this work for PanScan, PanC4 and PANDoRA. Each study participating in PanScan and PanC4 obtained approval from the responsible institutional review board (IRB) and IRB certification permitting data sharing in accordance with the NIH Policy for sharing of Data Obtained in NIH-Supported or NIH-Conducted Genome Wide Association Studies. The PANDoRA study protocol was approved by the Ethics Commission of the Medical Faculty of the University of Heidelberg. In accordance with the Declaration of Helsinki, written informed consent was obtained from each participant. FinnGen and JaPAN (meta-analysis of JaPAN consortium, BioBank Japan and National Cancer Center GWASs) summary statistics were used in this study. FinnGen has the permission to use samples from Finnish biobanks and data from national health registers for research. Each sample is coded and individual data will not be released. The project was evaluated by the Coordinating Ethics Committee of the Helsinki and Uusimaa Hospital District. FinnGen adhere to the Biobank Law, the Personal Data Act and EU Data Protection Regulation. JaPAN consortium GWAS study protocol was approved by the Ethical Review Board of Aichi Medical University, the Institutional Ethics Committee of Aichi Cancer Center, the Human Genome and Gene Analysis Research Ethics Committee of Nagoya University, and the ethics committees of the participating hospitals. BioBank Japan GWAS protocol was accepted by the ethics committees of the RIKEN Center for Integrative Medical Sciences. The informed consent for each participant was collected following the corresponding institutional ethics committee guidelines. National Cancer Center GWAS project was approved by the ethics committee of the National Cancer Center.
: Not applicable.
: The authors declare that they have no competing interests.