Funding for this research was provided by:
Major special projects in the 14th five-year plan (2021YFC2501100)
National Natural Science Foundation of China (82071296)
Received: 23 October 2021
Accepted: 9 February 2022
First Online: 1 March 2022
: The work was approved by the Institutional Review Board of Tiantan Hospital (KY2017-076-01).
: Written informed consents will be obtained from their legally authorized representatives. Privacy of patient will be effectively protected.
: All authors certify that we have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript.