Funding for this research was provided by:
Consejo Nacional de Ciencia y Tecnología (NA)
Received: 31 January 2020
Accepted: 18 June 2020
First Online: 2 July 2020
Ethics approval and consent to participate
: All study participants have provided inform consent and ethical approval for this study was gained from the University of Birmingham (ERN_16–0806).
: MC is a National Institute for Health Research (NIHR) Senior Investigator and receives funding from the National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre, the NIHR Surgical Reconstruction and Microbiology Research Centre and NIHR ARC West Midlands at the University of Birmingham and University Hospitals Birmingham NHS Foundation Trust, Health Data Research UK, Innovate UK (part of UK Research and Innovation), Macmillan Cancer Support, UCB Pharma. The views expressed in this article are those of the author(s) and not necessarily those of the NIHR, or the Department of Health and Social Care.DK reports grants from NIHR, grants from Innovate UK, grants from NIHR Birmingham Biomedical Research Centre, grants from NIHR SRMRC at the University of Birmingham and University Hospitals Birmingham NHS Foundation Trust, personal fees from Merck, personal fees from GSK, grants from Macmillan Cancer Support, outside the submitted work.