Funding for this research was provided by:
Baxalta US Inc., a Takeda company, Lexington, MA, USA (Baxalta US Inc., a Takeda company, Lexington, MA, USA)
Received: 8 December 2020
Accepted: 8 May 2023
First Online: 14 July 2023
: AO and DI are former employees of Baxalta US Inc., a Takeda company. CH and BE are employees of Takeda Development Center Americas, Inc. AMR, SP, RK, and VA are employees of IQVIA (formerly QuintilesIMS), a global provider of healthcare information and contract research services. MS has received speaker fees and advisory board honoraria from Takeda and research grants from Baxalta, a Takeda company, and Shire, a Takeda company.
: The study was reviewed and approved by a central institutional review board in the US (Western IRB) and by the Health Research Authority and Health and Care Research Wales and the East Midlands–Derby Research Ethics Committee in the UK. All patients provided informed consent and legally authorized representatives of participating adolescents provided informed consent on the adolescent’s behalf.
: Not applicable.