Received: 12 December 2020
Accepted: 23 August 2021
First Online: 19 October 2021
: Patients gave their written informed consent to the management of their sensitive data for scientific research each time they entered the Hospital. Local Ethical Committees approval was obtained: Comitato Etico Milano Area 2. Protocol N 2.0 BQ. 265_2017, 13 June 2017 for IRCCS Fondazione Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy. Comitato Etico San Raffaele; Studio clinico 2.0 BQ, version 4.0, 8 August 2019, for IRCCS Istituto Ortopedico Galeazzi, Milan; and IRCCS Policlinico San Donato, San Donato Milanese (MI).
: • Francesco Sardanelli has received research grants from and is a member of the speakers’ bureau and of the advisory group for General Electric. In addition, Francesco Sardanelli is the Editor-in-Chief of <i>European Radiology Experimental</i>; for this reason, he was not involved in any way in the revision/decision process, which was completely managed by the Deputy Editor, Dr. Akos Varga-Szemes (Medical University of South Carolina, Charleston, SC, USA).• Luca Rinaudo, former working in Academic University Politecnico of Turin and now employed at the commercial company “TECHNOLOGIC S.r.l”, has extracted and tabulated the densitometric data and has applied the mathematical algorithms based on the finite element analysis to calculate the Bone Strain Index. TECHNOLOGIC S.r.l. provided support in the form of salary for author LR but did not have any role in the study design, data collection and analysis, decision to publish or preparation of the manuscript.• Luca Maria Sconfienza is a member of the <i>European Radiology Experimental</i> Editorial Board. He has not taken part in the review or selection process of this article.• All remaining authors declare that they have no competing interests.