Received: 20 March 2021
Accepted: 18 August 2021
First Online: 7 January 2022
: Data were used from the POET study, a pragmatic randomized multicenter open-label controlled trial. Ethical approval for the study was granted by the Committee on Research Involving Human Subjects, region Arnhem—Nijmegen (Commissie Mensgebonden Onderzoek regio Arnem—Nijmegen). Local feasibility was approved by the Ethical Committees of all participating hospitals. The study was conducted in accordance with Good Clinical Practice guidelines and the Declaration of Helsinki. Written informed consent was obtained from all study patients.
: Not applicable.
: The authors declare that they have no competing interests.