Funding for this research was provided by:
F. Hoffmann-La Roche
Received: 21 May 2019
Accepted: 15 November 2019
First Online: 4 December 2019
Ethics approval and consent to participate
: The FUNCTION and LITHE study protocols were approved by an ethics committee or institutional review board at each participating center before the start of the study. All patients provided written informed consent in accordance with the Declaration of Helsinki.
: Not applicable.
: K Tuckwell and M Townsend are employees of Genentech, Inc. C Gabay has received research funding from Roche, Pfizer, and AB2 Bio and fees as consultant and speaker from Roche, Pfizer, AbbVie, Novartis, and Sanofi. T Sornasse was an employee of Genentech, Inc., at the time of the study. R Laubender is an employee of Roche Diagnostics GmbH. J Wang is an employee of Roche Products Ltd.