Received: 17 July 2020
Accepted: 1 September 2020
First Online: 19 October 2020
Ethics approval and consent to participate
: The protocol conforms to the principles of the declaration of Helsinki and was approved by the ethic committee of the Medical faculty of the University of Wuerzburg (reference number: 173/15_mm). All patients have to give their written consent on study participation. Patients, who are not able to give their written informed consent, are substituted by their legal representatives. Patients and/or their representatives need to be informed about the study in detailed fashion by their treating physician and must obtain sufficient time for consideration. Specific risks of the particular interventions were explained by the responsible specialists (DBS operation: neurosurgeon, general anesthesia: anesthesiologist).
: Not applicable.
: CD and UM report no conflict of interests<i>.</i> FS reports grants and personal fees from Boston Scientific, Abbott and Medtronic. CM received lecture honoraria by Boston Scientific. PC reports consultancy works for Brainlab and ProPhase. He received honoraria from Boehringer Ingelheim, Boston Scientific, Brainlab, Desitin and the DSO. PUH reports research grants from German Ministry of Research and Education, German Research Foundation, European Union, Charité – Universitätsmedizin Berlin, Berlin Chamber of Physicians, German Parkinson Society, University Hospital Würzburg, Robert Koch Institute, German Heart Foundation, Federal Joint Committee (G-BA) within the Innovationfond, University Hospital Heidelberg (within RASUNOA-prime; supported by an unrestricted research grant to the University Hospital Heidelberg from Bayer, BMS, Boehringer-Ingelheim, Daiichi Sankyo), Charité – Universitätsmedizin Berlin (within Mondafis; supported by an unrestricted research grant to the Charité from Bayer), University Göttingen (within FIND-AF randomized; supported by an unrestricted research grant to the University Göttingen from Boehringer-Ingelheim), outside the submitted work. JV received consulting and lecture fees from Boston Scientific, Medtronic and Newronika. Research grants from the German Research Foundation, the German Ministry of Research and Education, Boston Scientific and Medtronic. Lecture Honoraria from UCB, Zambon, Abbott.