Ahmad, Manar A.
Ghaleb, Sherien Salah
Hassan, Dalia Abd Elwahab
Sharkawi, Souty M. Z.
Abdelghany, Asmaa K.
Mostafa, Asmaa Mahmoud
Hassan, Randa M.
Abdalla, Ahmed G. Sobhi
Funding for this research was provided by:
Beni-Suef University (ID# BSU-CP7-19001)
Article History
Received: 23 June 2023
Accepted: 28 February 2024
First Online: 9 March 2024
Declarations
:
: Ethics guidelines were provided for this experiment by the Institutional Animal Care and Use Committee at Beni-Suef University (BSU-IACUC) (permission No. 021-204).
: Thirty male mice were separated to three equally sized groups indiscriminately: the control group: received no treatments, the AB-PINACA-treated group, and the MDMB-4en-PINACA-treated group. Treated groups exposed to the two herbs for two consecutive days via inhalation to simulate natural human exposure. Cannabinoid tetrad tests and anxiety-like behavior were performed. Serum samples were obtained for cardiac enzymes measurement. Heart and brain tissue samples were harvested for the determination of oxidative stress markers, brain neurotransmitters, and histopathological findings.
: Not applicable.
: The authors declare that they have no competing interests.