Shang, Qinghua
Gao, Wenhui
Zhang, Xiangting
Zhao, Jianqing
Wu, Ying
Li, Haoqi
Zhou, Ming
Fu, Zhen F.
Zhang, Chengguang
Zhao, Ling
Funding for this research was provided by:
Guangdong Major Project of Basic and Applied Basic Research (2020B0301030007)
Article History
Received: 30 January 2024
Accepted: 31 March 2024
First Online: 17 May 2024
Declarations
:
: All mouse studies were conducted at the Laboratory Animal Center of Huazhong Agricultural University, and the mice were fed in specific pathogen-free (SPF) environments. During the <i>Bb</i> challenge study, the mice with a body weight decrease of more than 25%, severe paralysis, or inability to feed were euthanized by CO<sub>2</sub>. The experimental protocol was reviewed and approved by the Scientific Ethics Committee of Huazhong Agricultural University with the approval number HZAUMO-2020–0096. The dogs and cats used in this study were fed in isolation environments as recommended by the Regulations for the Administration of Affairs Concerning Experimental Animals of the Ministry of Science and Technology of China. The immunization and challenge of <i>Bb</i> experiments were performed using protocols that were approved by the Scientific Ethics Committee of Huazhong Agricultural University (permit numbers: HZAUCA-2020-002 and HZAUDO-2020–003).
: Our research paper agreed to be published in Animal Diseases.
: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this study. Author Ling Zhao was not involved in the journal’s review or decisions related to this manuscript.