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Development of a PBPK Model for Lamotrigine which Incorporates Metabolism by UGT2B10: Impact of UGT2B10 Poor Metabolizer Phenotype and Pregnancy

Published Online: 2025-02-04

Authors

Gardner, Iain https://orcid.org/0000-0002-4811-8513
Heikkinen, Aki T.

Tang, Lloyd Wei Tat

Lapham, Kimberly

Goosen, Theunis C.
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Text and Data Mining valid from 2025-02-04

Version of Record valid from 2025-02-04
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Article History

Received: 15 November 2024

Accepted: 15 January 2025

First Online: 4 February 2025

Declarations

:

: IG and ATH are employees of Certara Predictive Technologies and may own Certara Stock. LWTT, KL and TCG are employees of Pfizer Inc., New York, NY, USA and may own shares/stock options in Pfizer Inc., New York, NY, USA.

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