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Considerations in Kp,uu,brain-based Strategy for Selecting CNS-targeted Drug Candidates with Sufficient Target Coverage and Substantial Pharmacodynamic Effect

Crossref DOI link: https://doi.org/10.1208/s12248-025-01035-8

Published Online: 2025-02-28

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Zou, Ling

Chien, Huan-Chieh

Pade, Devendra

Li, Yanfei

Nguyen, Minhkhoi

Bhamidipati, Ravi Kanth

Wang, Zhe

Enogieru, Osatohanmwen Jessica

Wahlstrom, Jan https://orcid.org/0000-0002-9434-1302
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Text and Data Mining valid from 2025-02-28

Version of Record valid from 2025-02-28
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Article History

Received: 26 November 2024

Accepted: 4 February 2025

First Online: 28 February 2025

Declarations

:

: The authors are Amgen Inc. employees and own stock or stock options. We declare that we have no conflict of interest.

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