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Application of a Modified In Situ Perfusion Model to Quantify Intestinal Drug Excretion and Transporter-Mediated Interactions after Intravenous Administration

Crossref DOI link: https://doi.org/10.1208/s12248-026-01221-2

Published Online: 2026-03-11

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Sun, Rongjin https://orcid.org/0000-0002-6694-4501
Li, Li https://orcid.org/0000-0003-2280-3755
Wang, Lu https://orcid.org/0000-0002-8643-6790
Xie, Zuoxu https://orcid.org/0000-0003-3977-4006
Bui, Dinh https://orcid.org/0000-0003-2161-5664
Zheng, Zicong https://orcid.org/0000-0002-2562-3453
Zhao, Xiaofeng https://orcid.org/0000-0003-2786-7416
Hao, Jia https://orcid.org/0009-0006-2210-3432
Chen, John https://orcid.org/0009-0001-0026-0887
Yin, Taijun https://orcid.org/0009-0008-0826-4680
Hu, Yiding https://orcid.org/0009-0003-3009-9435
Lai, Yurong https://orcid.org/0000-0001-9505-333X
Hu, Ming https://orcid.org/0000-0002-2744-6294
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Text and Data Mining valid from 2026-03-11

Version of Record valid from 2026-03-11
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Article History

Received: 13 September 2025

Accepted: 11 February 2026

First Online: 11 March 2026

Declarations

:

: Not applicable.

: Not applicable.

: The authors declare that they have no competing interests. Dr. Ming Hu is a co-founder of Sanarentero LLC. Yiding Hu, Yurong Lai, Xiaofeng Zhao, Jia Hao, John Chen are employees of Gilead Sciences Inc.