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Integrating In-vitro Permeability Assays within PBPK Modeling to Predict CNS Distribution of Standard and Engineered Antibodies

Crossref DOI link: https://doi.org/10.1208/s12248-026-01233-y

Published Online: 2026-04-18

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Kim, Seunghyun https://orcid.org/0009-0001-4392-0128
Lessard, Etienne https://orcid.org/0000-0002-4431-6475
Ling, Binbing https://orcid.org/0009-0000-6051-9590
Rennie, Kerry https://orcid.org/0000-0001-9216-2514
Haqqani, Arsalan https://orcid.org/0000-0003-2454-8989
Maharaj, Anil R. https://orcid.org/0000-0002-0475-6265
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Text and Data Mining valid from 2026-04-18

Version of Record valid from 2026-04-18
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Article History

Received: 8 December 2025

Accepted: 7 March 2026

First Online: 18 April 2026

Declarations

:

: The authors declare that they have no conflict of interest.