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Article History

Received: 4 July 2019

First Online: 13 April 2020

Disclosures

: James C. Cusack reports grants from Lumicell Inc. outside the submitted work. Carla Harmath serves on the medical advisory council of Accumen. Hedy Kindler reports personal fees and non-financial support from Inventiva, AstraZeneca, Boehringer Ingelheim, Merck, and Paredox; personal fees from Aldeyra Therapeutics, Bayer, BMS, Erytech, Five Prime Therapeutics, Ipsen Pharmaceuticals, Kyowa, and MedImmune; and funds to support clinical trials at her institution from Aduro, AstraZeneca, Bayer, BMS, Deciphera, GSK, Lilly, Merck, MedImmune, Polaris, Verastem, and Blueprint, all outside the submitted work. Chih-Yi Liao reports personal fees from Eisai, Exelixis, and Klus Pharma outside the submitted work. Garrett M. Nash reports non-financial support from Intuitive, outside the submitted work. Aytekin Oto reports grants from Philips Healthcare, Guerbet, and Profound Healthcare, and serves as a medical advisory board member for Profound Healthcare, all outside the submitted work. Nita Ahuja reports grant funding from Cepheid and Astex, has served as a consultant to Ethicon, and has licensed methylation biomarkers to Cepheid. Jesus Esquivel reports personal fees from Eight Medical. The remaining authors disclosed no conflicts of interest.