Cai, Zerong
Bai, Feiyu
Liu, Xuanhui
Wang, Zhangjie
Liu, Ziyang
Chen, Yufeng
Wu, Xiaojian
Funding for this research was provided by:
National High-Level Talents Program
National Key Clinical Discipline
National Natural Science Foundation of China (No.82573589)
the Science and Technology Project of Guangzhou (No.202201011382)
Guangzhou Key Research and Development Program (202206080008)
the program of Guangdong Provincial Clinical Research Center for Digestive Diseases (2020B1111170004)
Article History
Received: 8 July 2025
Accepted: 2 November 2025
First Online: 15 November 2025
Disclosure
: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
: Our study was registered in the ClinicalTrials.gov (NCT06808308) and was conducted in accordance with the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) 38 and received approval from the Ethics Committee of the Institutional Review Board of the Sixth Affiliated Hospital of Sun Yat-sen University (2025ZSLYEC-050).